Advanced functional nanomaterials for precise cancer diagnosis - nanoCANdi

Project summary

NanoCANdi develops new functional materials and biosensing microtechnology for cancer diagnosis. The project designs and manufactures large magnetic moment nanostructures with unique spin configurations for biomedical applications, specifically optimized for ultra-high sensitive giant magnetoresistance biosensors by micromagnetic modelling of both nanostructures and sensors. It addresses a key strategy in the fight against cancer: the early-stage detection of the disease. A crucial feature in this strategy is the specific biorecognition of cancer indicators. NanoCANdi undertakes this key point creating exclusive aptamers for a precise immobilization of cancer biomarkers, developing an innovative aptakiss/aptaswitch selection approach. The project expands new technologies and materials, producing biosensing devices that will impact the healthcare system with the adoption of precise medicine, letting physicians to detect and monitor treatments with reliable and affordable biochips.