Antibacterial breathable wound dressing based on polymer electrospun nanofibers - LIGNP4WOUND

Project summary

An increasing number of persons show difficulties for wound healing and the resistance of an increased number of pathogens to antibiotics or other drugs also makes the skin wound healing process more complicated. In parallel, more care is given to the cytotoxicity of biocides or compounds used in medical implants or dressings and the impact on the environment after their disposal. The LIGNP4WOUND addresses all these problems by adding natural biocides (lignin and chitosan) and bioactive molecules to the biodegradable nanofibrous mats made by electrospinning. Besides, solid lipid particles loaded with antibiotics will be tested as another option. The proposed wound dressings are composite materials and their performance will strongly depend on the adhesion and cohesion of the various composite parts. Thus, one of the project objectives is to use environmentally friendly plasma chemical technologies to achieve the desired stability of the final composite material.