Bioactive injectable hydrogels for soft tissue regeneration after reconstructive maxillofacial surgeries - INJECT-BIO

Project summary

Oral soft tissue regeneration after ablative surgery or trauma is still a challenging goal in today’s clinical routine. Currently available biomaterials in the market act as soft tissue fillers, but cannot ensure the bioactive response and/or ingrowth of gum-derived cells. In INJECT-BIO project, the development of advanced biomaterials and drug delivery systems for oral soft tissue regeneration will be investigated by applying Halomanas levan and bacterial cellulose-based injectable hydrogels containing IGF-1 and cannabis extract/cannabidiol liposomal simultaneous delivery systems. The project consortium unites the expertise, complementary skills and infrastructure of researchers and professionals from 5 countries – Latvia, Lithuania, Israel, Turkey and Czech Republic. The INJECT-BIO project will generate advanced know-how and knowledge of hydrogel-cell interactions leading the product till TRL4, giving a great potential for INJECT-BIO results to be transferred in the market.