Biogenic Inks combining marine collagen and ionic-doped calcium phosphates for bone tissue engineering - BiogenInk

Project summary

BiogenInk aims the development of bioinspired and bioresorbable inks for additive manufacturing, composed of marine collagen and ionic-doped calcium phosphates, as building blocks for the production of advanced scaffolds towards bone regeneration, promoting innovation in health sector, mainly on orthopaedic therapies. It is pretended to establish a sustainable and eco-friendly raw materials pipeline, including the production of a novel biological collagen crosslinker from a combined bioremediation strategy, which specific formulations mimics bone tissue composition. These printing materials will be further used to develop functional scaffolds, based in real clinical cases, recapitulating the complexity of bone structures obtained through a reverse engineering approach. A simple and standardized procedure from acquisition of imaging data to the production of patient case-specific biomaterials by 3D printing will be established, with potential to be successfully translated into clinics.