High resolution roll-to-roll printing of biocompatible graphene/protein multilayers for biomedical applications - BIOGRAPHY

Project summary

The functionality of many biosensors is based on electrode structures on which proteins are immobilised. High electrical conductivity and outstanding electrocatalytic properties make graphene the ideal electrode material for impedimetric and electrochemical biosensors. BIOGRAPHY aims at printing graphene electrodes with biofunctional coatings on large-area polymer foils in a roll-to-roll process, similar to the printing of newspapers, thus establishing a highly cost effective mass fabrication process for graphene-based biosensors. Developments include - a biocompatible, electrically conductive graphene ink for rotogravure printing, - a fabrication method for micro (< 10 µm) patterning of gravure printing cylinders, - a roll-to-roll process and production line for surface functionalization of large-area polymer foils by gravure printing of a micro-patterned graphene/protein multilayer, - proof of suitability of the printed multilayer for two different biosensor applications.